More evidence is showing a direct link between stress and the chronic activation of mast cells. This is from an article over at michiganradio.org. This could potentially shift the focus to treating the underlying traumas and doctors being more open to the idea of prescribing an anti anxiety drug.
Benzodiazapines are on the approved mast cell disease treatment list, by the way. Make sure you talk to your doctor first (preferably a mast cell specialist).
From the article:
A new study from Michigan State University reveals an important mechanism in stress related illness. It’s well-known that both physical and psychological stress are factors in a range of illnesses, including inflammatory and allergic diseases like irritable bowel syndrome, asthma, severe food allergies, and autoimmune disorders like lupus. Mast cells are a type of immune system cell believed to be involved in the development of these illnesses. The study showed that a specific receptor on the surface of the mast cell is activated under stress conditions, leading to the release of chemicals like histamine that can cause stress-related illness.
It’s not just histamine, either! The mast cell has dozens of molecule chemical mediators that can dump out. Heparin, chemokines, cytokines, TNFa, etc.
Moeser says that many diseases have both a genetic and psychological basis. A genetic predisposition can set someone up for illness, but in many cases that is not sufficient for them to develop disease. “If you are exposed to a stress, which is often referred to as a second hit, now those two combinations often work together to create disease.”
Based on these research results, in addition to recommending therapy and lifestyle changes, doctors may be able to prescribe a treatment that dials down the excessive stress response of the mast cells.
This highlights how important it is to destress and try to think of it as medicine rather than a luxury.